Comparison of salbutamol given by intermittent positive-pressure breathing and pressure-packed aerosol in chronic asthma.

نویسندگان

  • P B Anderson
  • A Goude
  • M D Peake
چکیده

A double-blind crossover study was performed to compare 4 . 8 mg salbutamol given by pressure-packed aerosol and intermittent positive-pressure breathing nebulization in chronic asthmatic patients. The two delivery techniques produced similar changes in respiratory function and pulse rates. Given equal effect, a high-dose pressure-packed aerosol would have advantages in cost and convenience over nebulization techniques.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Intravenous or inhaled salbutamol in severe acute asthma?

Ten patients with life-threatening attacks of asthma (status asthmatiucus') were treated with salbutamol inhaled by intermittent positive pressure breathing, and their response in terms of rise in peak flow rate was measured. They were then given intravenous salbutamol and any further increment in peak flow was measured. Hydrocortisone treatment was started simultaneously and the responses to s...

متن کامل

Aerosol salbutamol administration by IPPB: lowest effective dose.

This study was conducted to determine whether small doses of salbutamol solution, aerosolised and delivered by intermittent positive-pressure breathing (IPPB), would be as effective as the 5 to 10 mg dose usually recommended for inhalational use. In nine asthmatic subjects we found that there was no significant difference between the peak bronchodilator effect of 1.0, 2.5, and 5.0 mg of salbuta...

متن کامل

The bronchodilator effect of salbutamol administered by IPPB to patients with asthma. A controlled comparison with isoproterenol and placebo.

The bronchodilator and cardiovascular activity of isoproterenol hydrochloride (Isuprel) 5.0 mg, Salbutamol 5.0 and 2.5 mg and saline administered by IPPB to 30 patients with chronic bronchial asthma were determined and compared. Equal doses of isoproterenol and Salbutamol had similar peak bronchodilator effect, but the peak effect was reached much earlier with isoproterenoL Salbutamol bad longe...

متن کامل

Isoetharinewith Phenylephrine Aerosol in Asthma

The bronchodilator effect of fenoterol hydrobromide (0.5, 1.25, and 2.5 mg) was compared with either isoproternol (2.8 mg) or isoetharine (5 mg) with phenylephrine (1.25 mg) in a double-blind placebo-controlled study. When delivered by an intermittent positive-pressure breathing device to 24 nonsmoking young adult asthmatic subjects, fenoterol produced significant improvement in forced expirato...

متن کامل

On the relief of bronchospasm and the induction of alveolar hyperventilation: a comparative study of nebulized bronchodilators by deep breathing and intermittent positive pressure.

The introduction of aerosol therapy1”2 with bronchodilator drugs has added much to the management of obstructive pulmonary insufficiency.’ It is thought to be superior to oral and parenteral administration although comparative controlled data is lacking on this point.3 Since the combination of aerosol bronchodilators administered with intermittent positive pressure breathing (IPPB) , superior r...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Thorax

دوره 37 8  شماره 

صفحات  -

تاریخ انتشار 1982